Pergolide
Pergolide
Pergolide (/pɜːrˈɡoʊlaɪd/ pur-GOH-lyde) is a long-acting dopamine agonist medication that was used to manage the symptoms of Parkinson's disease, classified as a nonergoline derivative.
Etymology
The term "Pergolide" is derived from the chemical name of the drug, which is pergolide mesylate. The name does not have a specific etymological origin.
Usage
Pergolide was primarily used to treat the symptoms of Parkinson's disease until it was withdrawn from the U.S. market in 2007 due to serious valvular damage. It works by stimulating dopamine receptors in the brain, which helps to improve motor function. However, it is still available in some countries for veterinary use, particularly for the treatment of Pituitary Pars Intermedia Dysfunction (PPID) in horses.
Related Terms
- Dopamine: A type of neurotransmitter, a chemical messenger that transmits signals in the brain and other areas of the body.
- Parkinson's disease: A neurodegenerative disorder that affects predominately dopamine-producing neurons in a specific area of the brain.
- Nonergoline: A class of drugs that are used as dopamine agonists.
- Pituitary Pars Intermedia Dysfunction (PPID): A disease that affects the pituitary gland in horses, causing it to produce excessive amounts of certain hormones.
See Also
External links
- Medical encyclopedia article on Pergolide
- Wikipedia's article - Pergolide
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