Lysergic acid 3-pentyl amide

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Lysergic acid 3-pentyl amide

Chemical structure of Lysergic acid 3-pentyl amide

Lysergic acid 3-pentyl amide (LS3P) is a chemical compound belonging to the class of lysergamides, which are derivatives of lysergic acid. This compound is structurally related to other well-known lysergamides such as lysergic acid diethylamide (LSD).

Chemical Structure

Lysergic acid 3-pentyl amide is characterized by the presence of a lysergic acid core with a 3-pentyl amide substitution. The chemical structure of LS3P is depicted in the adjacent image, showing the lysergic acid moiety linked to a pentyl group via an amide bond.

Pharmacology

The pharmacological properties of lysergic acid 3-pentyl amide are not as extensively studied as those of LSD. However, as a lysergamide, it is expected to interact with serotonin receptors, particularly the 5-HT2A receptor, which is known to play a significant role in the psychedelic effects of related compounds.

Synthesis

The synthesis of lysergic acid 3-pentyl amide involves the reaction of lysergic acid with a suitable pentylamine. This process typically requires careful control of reaction conditions to ensure the formation of the desired amide bond without degradation of the lysergic acid structure.

Potential Effects

While specific studies on LS3P are limited, it is hypothesized that its effects may be similar to those of other lysergamides, potentially inducing alterations in perception, mood, and cognition. The exact potency and duration of effects would depend on its affinity for serotonin receptors and its metabolic stability.

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Contributors: Prab R. Tumpati, MD