Opipramol
Opipramol (pronounced: oh-pee-prah-mol) is a type of pharmaceutical drug used primarily in the treatment of various mental disorders. It belongs to the class of tricyclic antidepressants (TCAs), although its mechanism of action is somewhat different from typical TCAs.
Etymology
The term "Opipramol" is derived from its chemical structure, which is composed of a dibenzazepine ring system with a propylamine side chain. The prefix "Opi-" is derived from the Greek word "opos", meaning juice or sap, and "-pramol" is a common suffix used in the naming of tricyclic antidepressants.
Pharmacology
Opipramol acts primarily as a sigma receptor agonist. It also has moderate antihistamine effects and likely possesses antiserotonergic properties as well. Unlike other TCAs, it does not inhibit the reuptake of serotonin or norepinephrine to any significant degree.
Medical Uses
Opipramol is used in the treatment of generalized anxiety disorder, panic disorder, and insomnia. It may also be used off-label for the treatment of other conditions, such as irritable bowel syndrome and certain types of chronic pain.
Side Effects
Common side effects of opipramol include drowsiness, dry mouth, constipation, and blurred vision. Less common side effects can include weight gain, sexual dysfunction, and increased heart rate.
See Also
External links
- Medical encyclopedia article on Opipramol
- Wikipedia's article - Opipramol
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