2C-T

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2C-T

Chemical structure of 2C-T
Animation of the 2C-T molecule

2C-T is a synthetic psychedelic compound of the phenethylamine class. It is a member of the 2C family of drugs, which are known for their psychoactive properties. 2C-T was first synthesized by the chemist Alexander Shulgin and is described in his book PiHKAL (Phenethylamines I Have Known And Loved).

Chemical Structure

2C-T is chemically known as 2,5-dimethoxy-4-methylthiophenethylamine. It is a derivative of phenethylamine, with methoxy groups at the 2 and 5 positions of the benzene ring and a methylthio group at the 4 position. This structure is similar to other compounds in the 2C series, such as 2C-B and 2C-I.

Pharmacology

2C-T acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor. This action is responsible for its psychedelic effects, which can include altered perception, mood, and cognition. The compound is known for its relatively long duration of action compared to other psychedelics in the 2C series.

Effects

The effects of 2C-T can vary significantly depending on the dose and individual sensitivity. Common effects include visual and auditory hallucinations, changes in thought patterns, and emotional shifts. Users may also experience physical effects such as increased heart rate, nausea, and muscle tension.

Legal Status

The legal status of 2C-T varies by country. In some jurisdictions, it is classified as a controlled substance, making its manufacture, sale, or possession illegal. In others, it may be unscheduled but still subject to regulation under analog laws.

Related Compounds

2C-T is part of a larger group of compounds known as the 2C series, which includes other substances such as 2C-B, 2C-I, and 2C-E. These compounds share a common phenethylamine backbone but differ in their substituents, leading to variations in their pharmacological profiles and effects.

See Also

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Contributors: Prab R. Tumpati, MD