Niaprazine

Niaprazine is a sedative-hypnotic drug sold in France under the brand name Nopron. It is used primarily as a treatment for insomnia and is classified as a non-benzodiazepine hypnotic. Niaprazine is also used off-label for the treatment of certain types of anxiety disorders.

Pharmacology

Niaprazine works by binding to the GABA receptors in the brain, which are responsible for inhibiting the activity of the central nervous system. This action results in a calming effect, which can help to induce sleep.

Side Effects

Common side effects of niaprazine include drowsiness, dizziness, and dry mouth. Less common side effects can include nausea, constipation, and changes in appetite or weight. In rare cases, niaprazine can cause serious side effects such as hallucinations, confusion, and severe allergic reactions.

Contraindications

Niaprazine should not be used by individuals with a known hypersensitivity to the drug. It is also contraindicated in individuals with severe liver or kidney disease, and in those with certain types of glaucoma.

Interactions

Niaprazine can interact with a number of other medications, including other sedatives, certain types of antidepressants, and some antihistamines. It is important to inform your healthcare provider of all medications you are currently taking before starting treatment with niaprazine.

See Also

• Benzodiazepine
• GABA
• Insomnia
• Anxiety disorders

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