Dobutamine
Dobutamine
Dobutamine (/doʊˈbjuːtəmiːn/) is a medication used in the treatment of cardiogenic shock and severe heart failure. It is a synthetic catecholamine.
Etymology
The term "Dobutamine" is derived from a combination of its chemical structure components: dopamine, butyl, and amine.
Usage
Dobutamine is primarily used in cases of acute but potentially reversible heart failure, such as during or after cardiac surgery, or during severe acute illness or heart attack. It is administered intravenously and works by stimulating the heart to increase output and circulation.
Mechanism of Action
Dobutamine is a direct-acting agent whose primary activity results from stimulation of the beta-1 adrenoceptors of the heart, increasing contractility and cardiac output. Since it does not act on beta-2 adrenoceptors, it does not have the risk of causing peripheral vasodilation.
Side Effects
Common side effects of Dobutamine include palpitations, chest pain, shortness of breath, fever, and nausea. More serious side effects may include allergic reactions, irregular heartbeat, and high blood pressure.
Related Terms
External links
- Medical encyclopedia article on Dobutamine
- Wikipedia's article - Dobutamine
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