2C-T-7

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A psychedelic phenethylamine of the 2C family


2C-T-7
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2C-T-7 is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and described in his book PiHKAL: A Chemical Love Story. 2C-T-7 is known for its psychedelic effects, which include alterations in perception, mood, and cognitive processes.

Chemical structure and properties

2C-T-7 is chemically known as 2,5-dimethoxy-4-(n)-propylthiophenethylamine. It is a member of the 2C family of phenethylamines, which are characterized by a phenethylamine backbone with methoxy groups at the 2 and 5 positions and various substituents at the 4 position. In the case of 2C-T-7, the substituent is a propylthio group.

Pharmacology

2C-T-7 acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound also has affinity for other serotonin receptors, contributing to its complex effects on the brain.

Effects

The effects of 2C-T-7 are similar to those of other psychedelics, such as LSD and psilocybin. Users report visual hallucinations, altered perception of time, and changes in mood and thought patterns. The intensity and duration of effects can vary depending on the dose and individual sensitivity.

History and legal status

2C-T-7 was first synthesized by Alexander Shulgin in the 1980s. It gained some popularity in the 1990s and early 2000s as a recreational drug. However, due to reports of adverse effects and fatalities, many countries have since classified 2C-T-7 as a controlled substance.

Safety and toxicity

The safety profile of 2C-T-7 is not well-established, and there have been reports of serious adverse effects, including fatalities, associated with its use. The compound can cause serotonin syndrome when combined with other serotonergic drugs, and its use is not recommended outside of a controlled research setting.

Related compounds

2C-T-7 is part of a larger group of compounds known as the 2C family, which includes other substances such as 2C-B, 2C-I, and 2C-E. These compounds share a similar chemical structure but differ in their pharmacological effects and potency.

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Contributors: Prab R. Tumpati, MD