Ibopamine

Ibopamine.svg

Ibopamine
Ibopamine.svg
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number
PubChem	1972
DrugBank	DB08982
ChemSpider	1900
KEGG	D04499

Ibopamine is a synthetic drug used primarily in the field of ophthalmology. It is a prodrug of epinine, which is a dopamine derivative. Ibopamine is used to induce mydriasis (dilation of the pupil) and is often employed in diagnostic procedures to evaluate intraocular pressure and other conditions of the eye.

Pharmacology

Ibopamine works by stimulating dopamine receptors in the eye, leading to the dilation of the pupil. This effect is useful in various diagnostic procedures, including the assessment of glaucoma and other ocular hypertension conditions. The drug is metabolized into epinine, which then exerts its pharmacological effects.

Clinical Uses

Ibopamine is primarily used in ophthalmic diagnostics. It is particularly useful in:

• Inducing mydriasis for fundus examination
• Evaluating intraocular pressure in patients suspected of having glaucoma
• Assessing the functionality of the anterior segment of the eye

Administration

Ibopamine is typically administered in the form of eye drops. The dosage and frequency depend on the specific diagnostic requirement and the patient's condition.

Side Effects

Common side effects of ibopamine include:

• Temporary blurred vision
• Mild eye irritation
• Increased intraocular pressure

Patients with a history of cardiovascular disease or hypertension should use ibopamine with caution, as it may exacerbate these conditions.

Contraindications

Ibopamine is contraindicated in patients with:

• Known hypersensitivity to the drug or its components
• Narrow-angle glaucoma

See Also

• Dopamine
• Mydriasis
• Glaucoma
• Ophthalmology