Domperidone
Domperidone
Domperidone (/dɒmˈpɛrɪdoʊn/) is a peripheral dopamine antagonist that is used as an antiemetic and gastroparesis agent. It is not available in the United States, but is available in other countries.
Etymology
The name "Domperidone" is derived from the Latin "domperire", which means "to dominate or to control". This is in reference to the drug's ability to control the symptoms of nausea and vomiting.
Pharmacology
Domperidone works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) located in the brain. This action prevents the brain from receiving nerve messages that would otherwise cause feelings of nausea or the urge to vomit.
Uses
Domperidone is primarily used to treat nausea and vomiting, as well as conditions such as gastroparesis where the stomach takes too long to empty its contents. It is also used in the treatment of Parkinson's disease to reduce the side effects of other drugs without worsening the symptoms of the disease.
Side Effects
Common side effects of Domperidone include dry mouth, headache, and abdominal cramps. In rare cases, it can cause serious side effects such as arrhythmia or sudden cardiac death.
Related Terms
External links
- Medical encyclopedia article on Domperidone
- Wikipedia's article - Domperidone
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