UR-144

UR-144

Chemical structure of UR-144

UR-144 is a synthetic cannabinoid that has been used in scientific research and is known for its psychoactive effects. It is a member of the cannabinoid class of compounds, which interact with the endocannabinoid system in the human body. UR-144 is often found in synthetic cannabis products, which are sometimes marketed as "legal highs."

Chemical Properties

UR-144 is chemically classified as a naphthoylindole, which is a subclass of synthetic cannabinoids. Its chemical structure is characterized by a naphthalene ring attached to an indole core, with a pentyl chain at the indole nitrogen. The chemical formula for UR-144 is C21H29NO, and it has a molecular weight of 311.47 g/mol.

Pharmacology

UR-144 acts as a potent agonist of the CB2 receptor, with a lower affinity for the CB1 receptor. This selectivity for the CB2 receptor is thought to contribute to its effects, which can include anti-inflammatory and immunomodulatory actions. However, like many synthetic cannabinoids, UR-144 can also produce psychoactive effects similar to those of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis.

Effects and Usage

The effects of UR-144 can vary depending on the dose and the individual. Common effects include euphoria, relaxation, and altered perception. However, it can also cause adverse effects such as anxiety, paranoia, and tachycardia. Due to these potential risks, UR-144 and other synthetic cannabinoids are often subject to legal restrictions in many countries.

Legal Status

UR-144 is classified as a controlled substance in several countries due to its potential for abuse and lack of accepted medical use. In the United States, it is listed as a Schedule I substance under the Controlled Substances Act. Other countries have similar regulations, reflecting concerns about the safety and health risks associated with its use.

Related Pages

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• Tetrahydrocannabinol