Doxylamine

Doxylamine (pronounced dox-ill-a-meen) is a first-generation antihistamine primarily used as a short-term sedative and in over-the-counter (OTC) products for the relief of insomnia and allergy symptoms.

Etymology

The term "Doxylamine" is derived from its chemical name, N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)-ethanamine.

Usage

Doxylamine is found in many OTC sleep aids and in combination with decongestants, analgesics, or alcohol. It is also used in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.

Mechanism of Action

Doxylamine works by blocking the effects of histamine, a substance in the body that causes allergic symptoms. It also has sedative properties which help to induce sleep.

Side Effects

Common side effects of Doxylamine include drowsiness, dry mouth, and urinary retention. More serious side effects can include confusion, hallucinations, and difficulty urinating.

Related Terms

• Antihistamine
• Insomnia
• Allergy
• Decongestant
• Analgesic
• Alcohol
• Vitamin B6
• Morning sickness
• Histamine

External links

• Medical encyclopedia article on Doxylamine
• Wikipedia's article - Doxylamine

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