Diacetolol
Diacetolol is a pharmacological agent that belongs to the class of beta blockers. It is a metabolite of acebutolol, a cardioselective beta blocker used in the treatment of hypertension and arrhythmia.
Pharmacodynamics[edit]
Diacetolol acts as a beta-adrenergic antagonist, blocking the action of epinephrine and norepinephrine on beta receptors. This results in a decrease in heart rate, cardiac output, and blood pressure. It is a non-selective beta blocker, meaning it blocks both beta-1 and beta-2 receptors.
Pharmacokinetics[edit]
Diacetolol is primarily excreted in the urine, with a half-life of approximately 10-12 hours. It is metabolized in the liver by the cytochrome P450 enzyme system.
Clinical Use[edit]
Diacetolol is used in the treatment of hypertension and arrhythmia. It may also be used in the management of angina pectoris, myocardial infarction, and heart failure.
Side Effects[edit]
Common side effects of Diacetolol include fatigue, dizziness, and bradycardia. Less common side effects may include gastrointestinal disturbances, sleep disturbances, and depression.
Contraindications[edit]
Diacetolol is contraindicated in patients with asthma, bradycardia, and heart block. It should be used with caution in patients with diabetes and peripheral vascular disease.
Interactions[edit]
Diacetolol may interact with other medications, including other beta blockers, calcium channel blockers, and digoxin.
See Also[edit]
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
