2C-T-16

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2C-T-16

Chemical structure of 2C-T-16

2C-T-16 is a synthetic psychedelic compound belonging to the 2C family of phenethylamines. It was first synthesized by the chemist Alexander Shulgin and is documented in his book PiHKAL (Phenethylamines I Have Known And Loved).

Chemical Structure

2C-T-16 is chemically known as 2,5-dimethoxy-4-(i)-propylthiophenethylamine. It is characterized by the presence of a methoxy group at the 2 and 5 positions of the phenyl ring, and a propylthio group at the 4 position. This structure is similar to other compounds in the 2C-T series, which are known for their psychedelic effects.

Pharmacology

2C-T-16 acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound's interaction with these receptors leads to alterations in perception, mood, and cognition.

Effects

The effects of 2C-T-16 are similar to those of other psychedelics, including visual and auditory hallucinations, altered sense of time, and changes in thought patterns. Users have reported both positive and negative experiences, with effects varying based on dosage, individual physiology, and environment.

Dosage and Administration

The dosage of 2C-T-16 can vary, but it is typically taken orally. The onset of effects usually occurs within 1 to 2 hours, with the peak lasting several hours. Due to its potency, precise dosing is important to avoid adverse effects.

Legal Status

The legal status of 2C-T-16 varies by country. In some jurisdictions, it is classified as a controlled substance, making its manufacture, sale, or possession illegal. In others, it may not be specifically regulated, though it could fall under analog laws.

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Contributors: Prab R. Tumpati, MD