Falintolol

Falintolol' is a pharmacological compound classified as a beta-adrenergic receptor antagonist, also commonly referred to as a beta blocker. This class of medication is primarily used in the management of various cardiovascular conditions, owing to its efficacy in reducing heart rate, decreasing blood pressure, and modulating the stress on the heart. By antagonizing the beta-adrenergic receptors, falintolol inhibits the action of endogenous catecholamines like epinephrine (adrenaline) and norepinephrine (noradrenaline), which are implicated in the body's 'fight or flight' response.

Pronunciation

Fa-lin-to-lol

Mechanism of Action

Falintolol operates by selectively blocking beta-adrenergic receptors in the heart and vascular smooth muscle. This blockade leads to a decrease in cardiac output, a reduction in heart rate, and lowered blood pressure, making it beneficial for patients with hypertension, angina pectoris, and other cardiovascular disorders. The specific subtype selectivity of falintolol (beta-1, beta-2, or non-selective) determines its range of therapeutic applications and potential side effects.

Therapeutic Applications

The clinical use of falintolol encompasses the treatment of high blood pressure (hypertension), prevention of angina pectoris (chest pain), management of cardiac arrhythmias (irregular heartbeats), and protection against myocardial infarction (heart attack) in individuals at high risk. Beta blockers like falintolol are also used in managing symptoms of heart failure, though their use is tailored to the specifics of each patient's condition.

Developmental and Clinical Status

As with any pharmaceutical agent, the development of falintolol involves rigorous clinical testing to ascertain its efficacy, safety, and potential side effects. The stages of clinical trials—from initial safety studies in humans (Phase I) to large-scale efficacy trials (Phase III)—determine its suitability for market approval. The current developmental status of falintolol would provide insight into its future availability and clinical application.

Related Terms

• Beta Blocker
• Cardiovascular Disease
• Hypertension
• Angina Pectoris
• Cardiac Arrhythmia

See Also

• Pharmacology of Cardiovascular Drugs
• Clinical Trials
• Drug Development Process
• Adrenergic System

External links

• Medical encyclopedia article on Falintolol
• Wikipedia's article - Falintolol

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