Arketamine
Arketamine
Arketamine (pronounced: ar-ket-a-meen) is a general anesthetic and a dissociative hallucinogen. It is the (R)-(−)-enantiomer of the drug ketamine, which is a mixture of equal parts arketamine and esketamine (S-(+)-ketamine).
Etymology
The term "arketamine" is derived from the chemical structure of the compound, specifically the aryl group (Ar-) and the ketamine base. The prefix "ar-" refers to the presence of an aryl group, while "-ketamine" is a reference to the parent compound, ketamine.
Pharmacology
Arketamine is less potent as an anesthetic and analgesic compared to its counterpart, esketamine. However, it has been found to be more neuroprotective and less likely to induce psychotomimetic side effects.
Medical Uses
Arketamine has been used for the induction of anesthesia in patients undergoing surgery. It has also been investigated for its potential use in the treatment of depression, pain, and neurodegenerative diseases.
Related Terms
- Anesthetic: A drug used to induce a loss of sensation or awareness.
- Dissociative: A class of drugs that distort perceptions of sight and sound and produce feelings of detachment.
- Hallucinogen: A substance that causes hallucinations, perceptions that have no basis in reality.
- Ketamine: A medication primarily used for starting and maintaining anesthesia.
- Esketamine: The S-(+)-enantiomer of ketamine, used in the treatment of treatment-resistant depression.
- Psychotomimetic: A drug that produces effects similar to a psychotic state.
- Neurodegenerative diseases: Diseases characterized by the progressive loss of structure or function of neurons, including death of neurons.
External links
- Medical encyclopedia article on Arketamine
- Wikipedia's article - Arketamine
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