Rasagiline
Rasagiline
Rasagiline (pronounced rah-sah-gill-een) is a medication used in the treatment of Parkinson's disease. It is classified as a monoamine oxidase B (MAO-B) inhibitor.
Etymology
The term "Rasagiline" is derived from the chemical name (R)-N-propargyl-1-aminoindan, with the suffix "-giline" indicating its function as a giline class drug, which are selective monoamine oxidase inhibitors.
Usage
Rasagiline is used alone or with other medications to treat the symptoms of Parkinson's disease such as shakiness (tremor), stiffness, and difficulty moving. It can also be used to reduce the amount of "off" time (periods of slow movement or stiffness) in people with Parkinson's.
Mechanism of Action
Rasagiline works by increasing the levels of certain chemicals in the brain to help improve symptoms of Parkinson's disease. It inhibits the activity of monoamine oxidase B, an enzyme in the brain that breaks down dopamine, a substance that sends messages in the nervous system. By inhibiting this enzyme, rasagiline allows for more dopamine to be available for nerve cells, improving nerve function and symptoms of Parkinson's disease.
Side Effects
Common side effects of rasagiline include headache, joint pain, depression, and flu-like symptoms. Serious side effects can include high blood pressure, hallucinations, and serotonin syndrome.
Related Terms
External links
- Medical encyclopedia article on Rasagiline
- Wikipedia's article - Rasagiline
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