25I-NB4OMe
Overview
25I-NB4OMe is a synthetic psychedelic compound that belongs to the NBOMe class of drugs. It is a derivative of the phenethylamine 2C-I and is known for its potent hallucinogenic effects. The compound is primarily used in research settings and has gained attention for its psychoactive properties.
Chemical Structure
25I-NB4OMe is chemically related to 2C-I, with the addition of a methoxy group at the 4-position of the benzyl ring. This modification enhances its affinity for the serotonin receptors, particularly the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects.
Pharmacology
25I-NB4OMe acts as a potent agonist at the 5-HT2A receptor, similar to other compounds in the NBOMe series. This receptor is a subtype of the serotonin receptor and plays a crucial role in the modulation of mood, perception, and cognition. The activation of 5-HT2A receptors by 25I-NB4OMe leads to altered sensory perception and hallucinations.
Effects
The effects of 25I-NB4OMe are similar to those of other psychedelic substances, such as LSD and psilocybin. Users report visual and auditory hallucinations, altered sense of time, and changes in thought patterns. The onset of effects typically occurs within 30 to 90 minutes after ingestion, with a duration of action lasting 6 to 10 hours.
Risks and Safety
25I-NB4OMe is associated with several risks, particularly when used recreationally. Due to its potency, there is a high risk of overdose, which can lead to severe adverse effects such as tachycardia, hypertension, seizures, and psychosis. The compound has been linked to several fatalities, underscoring the importance of caution and regulation.
Legal Status
The legal status of 25I-NB4OMe varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Researchers must obtain special licenses to study the compound in a laboratory setting.
Related Compounds
See Also
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