Piperoxan

Piperoxan is a histamine antagonist and alpha-adrenergic antagonist with antihypertensive properties. It was discovered at the Pasteur Institute in 1950 and was the first antihistamine to be discovered. Piperoxan is also used in scientific research to induce hypertension in animals.

History

Piperoxan was discovered at the Pasteur Institute in 1950 by Daniel Bovet, who was awarded the Nobel Prize in Physiology or Medicine in 1957 for his work on antihistamines. It was the first antihistamine to be discovered and was initially used to treat allergic reactions.

Pharmacology

Piperoxan is a histamine antagonist, meaning it blocks the action of histamine, a substance in the body that causes allergic symptoms. It is also an alpha-adrenergic antagonist, which means it blocks the action of certain chemicals that constrict blood vessels and increase blood pressure. This makes piperoxan useful for treating hypertension.

Uses

Piperoxan is used in scientific research to induce hypertension in animals. It is also used to study the effects of other drugs on blood pressure and heart rate.

Side Effects

Like all drugs, piperoxan can cause side effects. These can include dizziness, nausea, and headache. In rare cases, it can cause severe allergic reactions.

See Also

• Histamine antagonist
• Alpha-adrenergic antagonist
• Antihypertensive
• Hypertension
• Daniel Bovet
• Pasteur Institute

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