Bevantolol
Bevantolol is a beta blocker used in the treatment of hypertension and angina pectoris. It is a non-selective beta blocker that also has alpha-1 blocking activity.
Pharmacology
Bevantolol is a competitive antagonist at both beta-1 adrenergic receptors and beta-2 adrenergic receptors, providing non-selective beta blockade. It also has alpha-1 adrenergic receptor blocking activity which can result in vasodilation and decreased peripheral resistance.
Clinical Use
Bevantolol is used in the treatment of hypertension, a condition characterized by high blood pressure. It is also used in the management of angina pectoris, a type of chest pain caused by reduced blood flow to the heart.
Side Effects
Common side effects of Bevantolol include fatigue, dizziness, and shortness of breath. Less common side effects can include depression, sleep disturbances, and sexual dysfunction.
Contraindications
Bevantolol is contraindicated in patients with bronchial asthma, sinus bradycardia, second and third degree heart block, overt cardiac failure, and cardiogenic shock.
Drug Interactions
Bevantolol can interact with other medications, including other beta blockers, calcium channel blockers, and digoxin.
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