Methylergometrine
Methylergometrine
Methylergometrine (pronounced: meth-ill-er-go-met-rin), also known as Methylergonovine, is a medication primarily used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion, and also to aid in expulsion of retained products of conception after a missed abortion and to help deliver the placenta after childbirth.
Etymology
The term "Methylergometrine" is derived from its chemical structure. It is a semi-synthetic ergot alkaloid, where "ergot" refers to a group of fungi in the genus Claviceps. The "methyle" part of the name refers to the presence of a methyl group in its chemical structure, and "metrine" is derived from the Greek word "metra", meaning uterus, referring to its action on the uterine muscle.
Usage
Methylergometrine is used in the form of an injection or in tablet form. It acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions. Thus, it induces a rapid and sustained tetanic uterotonic effect which shortens the third stage of labor and reduces blood loss.
Side Effects
Common side effects of Methylergometrine include nausea, vomiting, and diarrhea. More serious side effects include severe high blood pressure, heart attack, and bleeding in the brain.
Related Terms
External links
- Medical encyclopedia article on Methylergometrine
- Wikipedia's article - Methylergometrine
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