Draquinolol

Draquinolol.svg

== Draquinolol ==

Draquinolol is a beta blocker medication primarily used in the treatment of hypertension (high blood pressure) and certain types of arrhythmias (irregular heartbeats). It works by blocking the effects of epinephrine (adrenaline) on the beta receptors in the heart, which helps to slow down the heart rate and reduce blood pressure.

Medical Uses

Draquinolol is prescribed for several cardiovascular conditions, including:

• Hypertension: By lowering blood pressure, Draquinolol helps to prevent complications such as stroke and heart attack.
• Arrhythmias: It is effective in managing irregular heartbeats, particularly atrial fibrillation and ventricular tachycardia.
• Angina pectoris: Draquinolol can help reduce the frequency and severity of chest pain associated with angina.

Mechanism of Action

Draquinolol is a non-selective beta blocker, meaning it blocks both beta-1 and beta-2 receptors. By inhibiting these receptors, it reduces the effects of sympathetic nervous stimulation on the heart and blood vessels. This leads to a decrease in heart rate, cardiac output, and the release of renin from the kidneys, ultimately lowering blood pressure.

Side Effects

Common side effects of Draquinolol include:

• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Fatigue
• Dizziness
• Cold extremities

Less common but more serious side effects can include:

• Bronchospasm in patients with asthma
• Heart failure
• Depression
• Sexual dysfunction

Contraindications

Draquinolol should not be used in patients with:

• Asthma or COPD
• Severe bradycardia
• Heart block greater than first degree
• Cardiogenic shock

History

Draquinolol was developed in the late 20th century as part of a new generation of beta blockers aimed at providing more effective management of cardiovascular conditions with fewer side effects. It was approved for medical use in several countries and has since become a standard treatment option for hypertension and arrhythmias.

See Also

• Beta blocker
• Hypertension
• Cardiac arrhythmia
• Angina pectoris

External Links

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