EAM-2201

EAM-2201 is a synthetic cannabinoid that has been identified in various herbal smoking blends. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body.

Chemical Structure and Properties

EAM-2201 belongs to the class of indole-based synthetic cannabinoids. Its chemical structure is similar to other synthetic cannabinoids such as JWH-018 and AM-2201. The molecular formula of EAM-2201 is C24H22N2O, and its IUPAC name is 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole.

Pharmacology

EAM-2201 acts as a full agonist at the CB1 receptor and CB2 receptor, which are the primary receptors in the endocannabinoid system. These receptors are involved in various physiological processes including pain sensation, mood, and memory. The binding affinity of EAM-2201 to these receptors is high, making it a potent synthetic cannabinoid.

Legal Status

The legal status of EAM-2201 varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. For example, in the United States, EAM-2201 is listed as a Schedule I controlled substance under the Controlled Substances Act.

Health Effects and Risks

The use of EAM-2201 has been associated with a range of adverse health effects. These can include tachycardia, hypertension, nausea, vomiting, and psychosis. Long-term use may lead to dependence and withdrawal symptoms. Due to its potency and the variability in the composition of herbal blends, the risk of overdose is significant.

Detection in Biological Samples

EAM-2201 can be detected in biological samples using various analytical techniques such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). These methods are used in forensic and clinical toxicology to identify the presence of synthetic cannabinoids in urine, blood, and other tissues.

See Also

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• JWH-018
• AM-2201

External Links

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