CUMYL-PICA
CUMYL-PICA
CUMYL-PICA is a synthetic cannabinoid that has been identified in various designer drug products. It is part of a class of compounds that are designed to mimic the effects of tetrahydrocannabinol (THC), the active component of cannabis. These substances are often used recreationally and can have potent psychoactive effects.
Chemical Structure
CUMYL-PICA is chemically classified as an indole-based synthetic cannabinoid. Its full chemical name is 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide. The structure of CUMYL-PICA includes an indole core, which is a common feature among many synthetic cannabinoids. The presence of a cyanobutyl group and a phenylpropan-2-yl group distinguishes it from other compounds in this class.
Pharmacology
Synthetic cannabinoids like CUMYL-PICA act as agonists at the cannabinoid receptors, primarily the CB1 receptor and CB2 receptor. These receptors are part of the endocannabinoid system, which plays a role in regulating mood, memory, appetite, and pain sensation. The binding affinity and efficacy of CUMYL-PICA at these receptors can lead to effects similar to those of THC, but often with greater potency and unpredictability.
Effects and Risks
The effects of CUMYL-PICA can include euphoria, altered perception, and relaxation. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, tachycardia, and in severe cases, psychosis or seizures. The use of synthetic cannabinoids has been associated with numerous health risks, and their legal status varies by region.
Legal Status
The legal status of CUMYL-PICA varies worldwide. In many countries, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies continue to monitor and update the legal status of synthetic cannabinoids as new compounds are identified and their effects are better understood.
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