Metaraminol
Metaraminol
Metaraminol (pronounced: met-uh-ram-in-ol) is a potent vasopressor and alpha-adrenergic agonist used in the treatment of hypotension, particularly in cases of septic shock and anaphylaxis.
Etymology
The term "Metaraminol" is derived from the Greek words "meta", meaning "beyond", "arama", meaning "defense", and "inol", a common suffix in organic chemistry indicating the presence of a hydroxyl (-OH) group.
Pharmacology
Metaraminol acts primarily on alpha-1 adrenergic receptors, causing vasoconstriction and an increase in systemic vascular resistance and arterial pressure. It also has minor beta-adrenergic activity, which can lead to a slight increase in heart rate.
Clinical Use
Metaraminol is used primarily in the treatment of hypotension, particularly in cases of septic shock and anaphylaxis. It is also used in some cases to treat Orthostatic hypotension.
Side Effects
Common side effects of Metaraminol include hypertension, tachycardia, and arrhythmia. Less common side effects can include anxiety, headache, and nausea.
Related Terms
- Vasopressor
- Alpha-adrenergic agonist
- Hypotension
- Septic shock
- Anaphylaxis
- Orthostatic hypotension
- Hypertension
- Tachycardia
- Arrhythmia
- Anxiety
- Headache
- Nausea
External links
- Medical encyclopedia article on Metaraminol
- Wikipedia's article - Metaraminol
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