Fluanisone

Fluanisone.svg

Fluanisone is a typical antipsychotic drug of the butyrophenone class. It is primarily used in veterinary medicine for its sedative and antiemetic properties. Fluanisone is often combined with fentanyl to produce a neuroleptanalgesic effect, which is useful in small animal surgery.

Pharmacology

Fluanisone works by blocking dopamine receptors in the brain, which helps to reduce symptoms of psychosis such as hallucinations and delusions. It also has antiemetic properties, making it useful in preventing nausea and vomiting.

Uses

In veterinary medicine, fluanisone is commonly used in combination with fentanyl for its sedative and analgesic effects. This combination is particularly useful in small animal surgery, providing both pain relief and sedation.

Side Effects

Common side effects of fluanisone include drowsiness, dry mouth, and constipation. In some cases, it may cause extrapyramidal symptoms such as tremors, rigidity, and bradykinesia. Long-term use can lead to tardive dyskinesia, a condition characterized by involuntary, repetitive body movements.

History

Fluanisone was first synthesized in the 1960s and has been used in veterinary medicine since then. It is not commonly used in human medicine due to the availability of newer antipsychotic drugs with fewer side effects.

See Also

• Antipsychotic
• Butyrophenone
• Dopamine receptor antagonist
• Veterinary medicine
• Neuroleptanalgesia

External Links

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