MN-18

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MN-18

Chemical structure of MN-18

MN-18 is a synthetic cannabinoid that has been used in scientific research. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. MN-18 is structurally related to other synthetic cannabinoids and is often studied for its effects on the central nervous system.

Chemical Properties

MN-18 is classified as an indole-based synthetic cannabinoid. Its chemical structure includes a core indole ring, which is a common feature among many synthetic cannabinoids. The specific chemical formula of MN-18 is C23H22N2O, and it has a molecular weight of 342.44 g/mol.

Pharmacology

MN-18 acts as a full agonist at the CB1 receptor and CB2 receptor, which are the primary receptors for cannabinoids in the body. These receptors are part of the G protein-coupled receptor family and are involved in a variety of physiological processes, including pain modulation, appetite regulation, and immune response.

The binding affinity of MN-18 to these receptors is high, which contributes to its potent effects. The activation of CB1 receptors by MN-18 can lead to psychoactive effects similar to those produced by tetrahydrocannabinol (THC), the active component of cannabis.

Effects and Uses

In research settings, MN-18 is used to study the effects of synthetic cannabinoids on the brain and body. It is often used in animal models to investigate the potential therapeutic and adverse effects of cannabinoid receptor activation.

The effects of MN-18 can include alterations in mood, perception, and cognition, as well as physiological effects such as changes in heart rate and blood pressure. Due to its potency, MN-18 is typically used in very small doses in research studies.

Legal Status

The legal status of MN-18 varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Researchers working with MN-18 must comply with relevant regulations and obtain appropriate licenses.

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Contributors: Prab R. Tumpati, MD