Flibanserin

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Flibanserin

Flibanserin (pronounced /flɪˈbænsərɪn/) is a non-hormonal prescription drug approved by the FDA for the treatment of premenopausal women with hypoactive sexual desire disorder (HSDD). The drug is sold under the trade name Addyi.

Etymology

The term "Flibanserin" is a blend of the words "flibber", which is a nonsensical word with no known meaning, and "serin", which is a type of finch. The name was likely chosen for its uniqueness and memorability.

Usage

Flibanserin is used to treat HSDD, a condition characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to a co-existing medical or psychiatric condition, problems within the relationship, or the effects of a medication or other drug substance.

Mechanism of Action

Flibanserin is a serotonin 1A receptor agonist and a serotonin 2A receptor antagonist, but the mechanism by which the drug improves sexual desire and related distress is not known. Flibanserin is taken once daily at bedtime.

Side Effects

Common side effects of Flibanserin include dizziness, sleepiness, nausea, fatigue, insomnia, and dry mouth. Flibanserin can cause hypotension and syncope; these risks are increased if Flibanserin is taken with alcohol or certain other medications.

Related Terms

External links

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