2C-T-21

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2C-T-21

2D structure of 2C-T-21
3D stick model of 2C-T-21

2C-T-21 is a synthetic psychedelic compound belonging to the 2C family of phenethylamines. It was first synthesized by the chemist Alexander Shulgin and is known for its psychoactive effects.

Chemical Structure

2C-T-21 is chemically classified as a phenethylamine, with the full chemical name 2,5-dimethoxy-4-(2-fluoroethylthio)phenethylamine. The compound features a phenyl ring with methoxy groups at the 2 and 5 positions, and a 2-fluoroethylthio group at the 4 position.

Pharmacology

2C-T-21 acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound is known to produce alterations in perception, mood, and cognition.

Effects

The effects of 2C-T-21 are similar to other psychedelics in the 2C family, including visual and auditory hallucinations, altered thought processes, and changes in emotional states. The duration of effects typically lasts between 6 to 10 hours, depending on the dose and individual metabolism.

Synthesis

The synthesis of 2C-T-21 involves the reaction of 2,5-dimethoxy-4-bromophenethylamine with 2-fluoroethanethiol, followed by purification processes. The synthesis requires careful handling of reagents and precise control of reaction conditions.

Legal Status

The legal status of 2C-T-21 varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be unscheduled. Users should be aware of the legal implications of possessing or distributing this compound.

Related Compounds

2C-T-21 is part of the broader 2C family, which includes other compounds such as 2C-B, 2C-I, and 2C-T-7. These compounds share a similar core structure but differ in their substituents, leading to variations in their pharmacological profiles and effects.

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2C-T-21

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Contributors: Prab R. Tumpati, MD