Tienoxolol
Tienoxolol is a beta-adrenergic receptor antagonist (beta-blocker) used in the management of hypertension and other cardiovascular conditions. It is known for its selective action on beta-1 adrenergic receptors, which are primarily located in the heart.
Pharmacology[edit]
Mechanism of Action[edit]
Tienoxolol works by blocking the beta-1 adrenergic receptors in the heart, leading to a decrease in heart rate and cardiac output. This action reduces the workload on the heart and lowers blood pressure. Unlike non-selective beta-blockers, Tienoxolol has minimal effects on beta-2 receptors, which are found in the lungs and vascular smooth muscle.
Pharmacokinetics[edit]
Tienoxolol is administered orally and is well absorbed from the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily in the urine. The drug has a half-life that allows for once-daily dosing, which can improve patient compliance.
Clinical Uses[edit]
Tienoxolol is primarily used in the treatment of hypertension. It may also be used in the management of angina pectoris and in the prevention of myocardial infarction.
Side Effects[edit]
Common side effects of Tienoxolol include bradycardia, fatigue, and dizziness. As with other beta-blockers, it may cause or exacerbate bronchospasm in susceptible individuals, such as those with asthma.
Contraindications[edit]
Tienoxolol is contraindicated in patients with bradycardia, heart block, and cardiogenic shock. Caution is advised in patients with diabetes mellitus and chronic obstructive pulmonary disease (COPD).
Related pages[edit]
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
