Dicycloverine
Medication used to treat intestinal cramping
Dicycloverine | |
---|---|
![]() | |
INN | |
Drug class | |
Routes of administration | |
Pregnancy category | |
Bioavailability | |
Metabolism | |
Elimination half-life | |
Excretion | |
Legal status | |
CAS Number | |
PubChem | |
DrugBank | |
ChemSpider | |
KEGG |
Dicycloverine, also known as dicyclomine, is a medication used to treat intestinal cramping and irritable bowel syndrome (IBS). It is classified as an anticholinergic and antispasmodic agent, which works by relaxing the smooth muscles of the gastrointestinal tract.
Medical uses
Dicycloverine is primarily used to alleviate symptoms associated with irritable bowel syndrome, such as abdominal pain and intestinal cramping. It is effective in reducing muscle spasms in the gastrointestinal tract, thereby providing relief from discomfort and pain. The medication is typically administered orally in the form of capsules or tablets.
Mechanism of action
Dicycloverine functions as an anticholinergic agent, meaning it blocks the action of the neurotransmitter acetylcholine on muscarinic receptors in the smooth muscle of the gastrointestinal tract. This action reduces muscle contractions and spasms, leading to decreased pain and discomfort in conditions like IBS.
Side effects
Common side effects of dicycloverine include dry mouth, dizziness, blurred vision, and nausea. Due to its anticholinergic properties, it may also cause urinary retention, constipation, and tachycardia. Patients are advised to use caution when engaging in activities that require mental alertness, such as driving.
Contraindications
Dicycloverine is contraindicated in individuals with myasthenia gravis, glaucoma, and obstructive uropathy. It should be used with caution in patients with prostatic hypertrophy and cardiovascular disease.
Pharmacokinetics
Dicycloverine is well absorbed from the gastrointestinal tract and reaches peak plasma concentrations within 1 to 2 hours after oral administration. It is metabolized in the liver and excreted primarily in the urine.
History
Dicycloverine was first introduced in the 1950s and has since become a widely used treatment for gastrointestinal disorders. Its development marked a significant advancement in the management of IBS and related conditions.
Related pages
Gallery
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Deepika vegiraju, Prab R. Tumpati, MD