Fallypride
Fallypride is a radiotracer that is used in positron emission tomography (PET) imaging. It is a high-affinity dopamine D2/D3 receptor antagonist, which allows it to be used in the study of diseases such as schizophrenia and Parkinson's disease, which are characterized by alterations in dopamine function.
Chemistry
Fallypride is a fluorine-18 labeled compound. It is a derivative of sulpiride, a D2/D3 receptor antagonist. The fluorine-18 label allows it to be detected by PET imaging.
Pharmacology
Fallypride binds to D2 and D3 receptors with high affinity, which allows it to be used as a radiotracer in PET imaging. It has a high selectivity for these receptors, which means it can provide a clear image of their distribution in the brain.
Clinical use
Fallypride is used in PET imaging to study the distribution and density of D2/D3 receptors in the brain. This can be useful in the study of diseases such as schizophrenia and Parkinson's disease, which are characterized by alterations in dopamine function. It can also be used to study the effects of drugs on these receptors.
Research
Research has shown that fallypride can be used to image D2/D3 receptors in the human brain with high resolution. This has made it a valuable tool in the study of diseases that affect dopamine function.
See also
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