JWH-120
Overview
JWH-120 is a synthetic cannabinoid that acts as a potent agonist at the cannabinoid receptors. It is part of the naphthoylindole family of compounds, which are known for their ability to mimic the effects of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis.
Chemical Structure
JWH-120 is characterized by its naphthoylindole structure, which includes a naphthalene ring linked to an indole moiety. This structure is crucial for its binding affinity to cannabinoid receptors, particularly CB1 and CB2 receptors.
Pharmacology
JWH-120 functions as a full agonist at both CB1 and CB2 receptors, with a higher affinity for the CB2 receptor. This selectivity makes it of interest in research focused on the immune system and inflammation, as CB2 receptors are primarily located in peripheral tissues and immune cells.
Mechanism of Action
Upon binding to cannabinoid receptors, JWH-120 activates the G-protein coupled receptor pathways, leading to the inhibition of adenylate cyclase and a decrease in cyclic AMP levels. This results in various downstream effects, including modulation of neurotransmitter release and immune response.
Potential Applications
Research into JWH-120 and similar compounds is ongoing, with potential applications in the treatment of pain, inflammation, and neurological disorders. However, due to its synthetic nature and potential for abuse, it is also a subject of regulatory scrutiny.
Legal Status
The legal status of JWH-120 varies by country. In many jurisdictions, it is classified as a controlled substance due to its psychoactive properties and potential for abuse. Researchers must comply with local regulations when studying this compound.
Safety and Toxicity
The safety profile of JWH-120 is not well-established, and its use outside of controlled research settings is not recommended. Potential side effects may include tachycardia, anxiety, and hallucinations, similar to other synthetic cannabinoids.
Related Pages
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
