FUB-APINACA

FUB-APINACA

FUB-APINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. FUB-APINACA is structurally related to other synthetic cannabinoids such as AB-FUBINACA and ADB-FUBINACA.

Chemical Structure and Properties

FUB-APINACA belongs to the indazole-3-carboxamide family of synthetic cannabinoids. Its chemical structure includes a fluorobenzyl group, which is attached to the indazole core. The full chemical name of FUB-APINACA is N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide.

Pharmacology

FUB-APINACA acts as a potent agonist at the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including pain sensation, mood, and appetite. The activation of these receptors by FUB-APINACA can lead to psychoactive effects similar to those produced by tetrahydrocannabinol (THC), the primary psychoactive component of cannabis.

Legal Status

The legal status of FUB-APINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. For example, in the United States, it is listed as a Schedule I controlled substance under the Controlled Substances Act.

Health Risks and Toxicity

The use of FUB-APINACA has been associated with a number of adverse health effects. These can include tachycardia, hypertension, nausea, vomiting, and hallucinations. In severe cases, it can lead to acute kidney injury and seizures. The long-term health effects of FUB-APINACA use are not well understood, but it is believed to pose significant risks due to its high potency and the potential for contamination with other harmful substances.

Detection in Biological Samples

FUB-APINACA can be detected in biological samples using various analytical techniques such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). These methods are used in forensic and clinical toxicology to identify and quantify the presence of FUB-APINACA in blood, urine, and other tissues.

See Also

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• AB-FUBINACA
• ADB-FUBINACA

References

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