Enadoline
Enadoline (pronounced: en-uh-doh-lin) is a type of analgesic drug that was developed in the 1990s by Eli Lilly and Company. It is known for its kappa opioid receptor agonist properties.
Etymology
The term "Enadoline" is derived from the chemical structure of the drug, specifically the presence of an enamide functional group and the indoline backbone.
Pharmacology
Enadoline acts as a kappa opioid receptor agonist. The kappa opioid receptors are one of the three types of opioid receptors found in the human body, the other two being the mu opioid receptor and the delta opioid receptor. Agonists of the kappa opioid receptor, like Enadoline, are known to produce analgesic effects.
Clinical Trials
In the 1990s, Enadoline was tested in human clinical trials as a potential analgesic. However, the trials were discontinued due to the occurrence of dysphoric side effects.
Related Terms
- Analgesic: A type of medication used to relieve pain.
- Kappa opioid receptor: One of the three types of opioid receptors in the human body. Agonists of this receptor are known to produce analgesic effects.
- Dysphoria: A state of unease or dissatisfaction with life.
See Also
External links
- Medical encyclopedia article on Enadoline
- Wikipedia's article - Enadoline
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