Tranylcypromine/trifluoperazine

From WikiMD's medical encyclopedia

Tranylcypromine/trifluoperazine is a combination medication used in the treatment of certain mental/mood disorders. The medication combines tranylcypromine, a monoamine oxidase inhibitor (MAOI), and trifluoperazine, a typical antipsychotic.

Indications

Tranylcypromine/trifluoperazine is indicated for the treatment of schizophrenia and other mental/mood disorders. It may also be used in the management of anxiety and depression.

Mechanism of Action

Tranylcypromine works by increasing the levels of certain chemicals in the brain that help elevate mood. Trifluoperazine works by decreasing abnormal excitement in the brain.

Side Effects

Common side effects of tranylcypromine/trifluoperazine include drowsiness, dizziness, and dry mouth. Serious side effects may include severe nervous system reaction, very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; agitation, hallucinations, nausea, vomiting, diarrhea, loss of appetite, feeling unsteady, loss of coordination; or high fever, sweating, confusion, fast or uneven heartbeats, rapid breathing, feeling like you might pass out.

Precautions

Before taking tranylcypromine/trifluoperazine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Interactions

Tranylcypromine/trifluoperazine can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works.

Dosage

Dosage of tranylcypromine/trifluoperazine is based on the patient's medical condition and response to treatment. It is important to follow your doctor's instructions carefully.

See Also

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Contributors: Prab R. Tumpati, MD