Butriptyline

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Butriptyline

Butriptyline (pronounced: bu-trip-ty-leen) is a tricyclic antidepressant (TCA) that was introduced in the 1960s by Hoffmann-La Roche for the treatment of depression. It is chemically related to amitriptyline and is classified as a secondary amine TCA.

Etymology

The term "Butriptyline" is derived from its chemical structure, which consists of a butyl group attached to the basic tricyclic structure common to all TCAs. The "-tyline" suffix is common to many TCAs, indicating their shared structural features.

Pharmacology

Butriptyline works by inhibiting the reuptake of serotonin and norepinephrine, two neurotransmitters that are involved in mood regulation. This increases the levels of these neurotransmitters in the brain, which can help to alleviate symptoms of depression.

Side Effects

Common side effects of butriptyline include dry mouth, constipation, blurred vision, and drowsiness. Like other TCAs, butriptyline can also cause cardiotoxicity in overdose.

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