Lavoltidine

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Lavoltidine (pronounced la-vol-ti-dine) is a histamine antagonist specifically a H2 receptor antagonist that was developed for potential use in the treatment of peptic ulcer disease and gastroesophageal reflux disease (GERD). However, its development was discontinued due to the discovery of adverse effects on the liver.

Etymology

The term "Lavoltidine" is derived from the Latin word "lavolta", meaning "to turn", and the suffix "-tidine", which is commonly used in the names of H2 receptor antagonists.

Pharmacology

Lavoltidine works by blocking the action of histamine on the parietal cells in the stomach, thereby reducing the production of gastric acid. This can help to prevent and heal peptic ulcers and reduce the symptoms of GERD.

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