Desipramine

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Desipramine

Desipramine (pronounced: de-SIP-ra-meen) is a type of medication known as a tricyclic antidepressant (TCA). It is primarily used in the treatment of depression and neuropathic pain.

Etymology

The term "Desipramine" is derived from its chemical name, desmethylimipramine. It is a secondary amine TCA, hence the "-amine" suffix. The prefix "des-" indicates the absence of a methyl group, which is present in its parent compound, imipramine.

Usage

Desipramine is used to treat symptoms of depression. It works by increasing the amounts of certain natural substances in the brain that are needed for mental balance. Desipramine is also effective in treating neuropathic pain, and may be used in the management of attention deficit hyperactivity disorder (ADHD) in certain cases.

Side Effects

Like all medications, desipramine can cause side effects. These may include dry mouth, blurred vision, constipation, weight gain, dizziness, and increased heart rate. More serious side effects can include arrhythmia, mania, and increased risk of suicide in individuals under 25.

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