Sympatholytic

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Sympatholytic

Sympatholytic (pronounced sim-puh-tho-LIT-ik) is a term used in medicine to describe drugs or substances that inhibit the postganglionic functioning of the sympathetic nervous system (SNS).

Etymology

The term "sympatholytic" is derived from the Greek words "sympatheia" meaning "sympathy" and "lysis" meaning "loosening".

Function

Sympatholytics are primarily used to treat conditions like hypertension, anxiety disorders, and glaucoma. They work by reducing the activity of the sympathetic nervous system, which is responsible for the body's "fight or flight" response. This can help to lower blood pressure, reduce heart rate, and decrease anxiety.

Types of Sympatholytics

There are several types of sympatholytic drugs, including:

  • Beta blockers: These drugs block the effects of adrenaline on the heart and blood vessels, slowing down the heart rate and reducing blood pressure.
  • Alpha blockers: These drugs block the effects of adrenaline on the smooth muscles of the blood vessels, causing them to relax and widen, which can lower blood pressure.
  • Centrally acting drugs: These drugs work in the brain to decrease the signals sent to the sympathetic nervous system.

Related Terms

  • Sympathomimetic: A drug or substance that mimics or enhances the effects of the sympathetic nervous system.
  • Parasympatholytic: A drug or substance that inhibits the postganglionic functioning of the parasympathetic nervous system.
  • Parasympathomimetic: A drug or substance that mimics or enhances the effects of the parasympathetic nervous system.

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