Sufotidine
Sufotidine is a histamine H2 receptor antagonist that is used in the treatment of gastrointestinal disorders. It is a type of drug that inhibits the action of histamine at the H2 receptors of the stomach, reducing the production of stomach acid.
Mechanism of Action
Sufotidine works by blocking the histamine H2 receptor on the cells of the stomach lining. This receptor is normally activated by histamine, a substance produced by the body that promotes acid secretion in the stomach. By blocking this receptor, Sufotidine prevents the activation of the stomach's acid-producing cells, thereby reducing the amount of acid produced.
Uses
Sufotidine is primarily used in the treatment of peptic ulcer disease and gastroesophageal reflux disease (GERD). It can also be used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome.
Side Effects
Like all medications, Sufotidine can cause side effects. These may include headache, dizziness, diarrhea, and rash. In rare cases, it can cause more serious side effects such as arrhythmia or pancreatitis.
Interactions
Sufotidine can interact with other medications, including anticoagulants, antifungals, and certain antidepressants. It is important to inform your healthcare provider of all medications you are taking to avoid potential interactions.
Precautions
Before taking Sufotidine, it is important to inform your healthcare provider if you have any allergies, kidney disease, liver disease, or other medical conditions. It is also important to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
See Also
- Histamine H2 receptor antagonist
- Gastrointestinal disorders
- Peptic ulcer disease
- Gastroesophageal reflux disease
- Zollinger-Ellison syndrome
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Contributors: Prab R. Tumpati, MD