Tiotropium bromide
Tiotropium Bromide
Tiotropium bromide (pronounced tee-oh-TROH-pee-um BROH-mide) is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.
Etymology
The name "Tiotropium" is derived from Greek roots "tio-" meaning sulfur and "-tropium" referring to its use as a tropane derivative. "Bromide" refers to the bromine atom included in its chemical structure.
Pharmacology
Tiotropium bromide works by relaxing the muscles around the airways in the lungs, helping them to stay open and making it easier to breathe. It is a type of drug called an anticholinergic (specifically a muscarinic receptor antagonist), and it blocks a certain type of neurotransmitter (acetylcholine) in the body, reducing bronchospasm.
Usage
Tiotropium bromide is used to control and prevent symptoms (such as wheezing, shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD, which includes bronchitis and emphysema). It is generally used once a day, inhaled through the mouth.
Side Effects
Common side effects of Tiotropium bromide include dry mouth and constipation. Serious side effects may include allergic reactions, eye problems (such as glaucoma), difficulty urinating, or chest pain.
Related Terms
- Bronchodilator
- Anticholinergic
- Chronic Obstructive Pulmonary Disease
- Asthma
- Muscarinic Receptor Antagonist
- Bronchospasm
External links
- Medical encyclopedia article on Tiotropium bromide
- Wikipedia's article - Tiotropium bromide
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