Lormetazepam

Lormetazepam is a drug that belongs to the Benzodiazepine class of medications. It is primarily used for the short-term treatment of sleeping disorders, and is also used in some surgical procedures where sedation is required.

Etymology

The name "Lormetazepam" is derived from the core chemical structure of the drug, which is a fusion of a benzene ring and a diazepine ring. The prefix "Lor-" is a common prefix used in the naming of benzodiazepines, and "metazepam" refers to the specific alterations made to the core benzodiazepine structure to create this particular drug.

Medical Uses

Lormetazepam is primarily used for the treatment of insomnia, particularly where the patient has difficulty falling asleep. It is also used in some surgical procedures to induce sedation and amnesia.

Side Effects

Like all benzodiazepines, Lormetazepam can cause a range of side effects. These can include drowsiness, dizziness, and impaired coordination. In some cases, it can also cause more serious side effects such as respiratory depression and psychological dependence.

Pharmacology

Lormetazepam works by enhancing the effect of the neurotransmitter GABA, which is involved in the regulation of sleep and anxiety. It does this by binding to specific sites on the GABA receptor, increasing the efficiency of this neurotransmitter and producing a sedative effect.

History

Lormetazepam was first synthesized in the 1970s as part of a wave of new benzodiazepine drugs. It has since become a commonly prescribed medication for insomnia and other sleep disorders.

See Also

• Benzodiazepine
• Insomnia
• GABA

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  Lormetazepam chemical structure

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  3D model of Lormetazepam

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  (R)-Lormetazepam structural formula

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  (S)-Lormetazepam structural formula