Climazolam
Climazolam is a benzodiazepine derivative drug with anxiolytic, anticonvulsant, hypnotic, amnestic, sedative, and muscle relaxant properties. It is a potent and short-acting drug, developed by a team at Hoffmann-La Roche in the 1970s.
Chemistry
Climazolam is a benzodiazepine, which is a class of drugs with a benzene ring fused to a diazepine ring. It is structurally related to other benzodiazepines such as diazepam and alprazolam.
Pharmacology
Climazolam acts on the GABA receptors in the brain, enhancing the effect of the neurotransmitter GABA. This results in sedative, anxiolytic, and muscle relaxant effects. It is metabolized in the liver and excreted in the urine.
Medical Uses
Climazolam is used in the treatment of severe insomnia and in anesthesia for surgical procedures. It is also used in the treatment of acute seizures and for the short-term relief of symptoms of anxiety.
Side Effects
Common side effects of climazolam include drowsiness, dizziness, and loss of coordination. Long-term use can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.
Legal Status
The legal status of climazolam varies by country. In some countries, it is a controlled substance, while in others it is available by prescription only.
See Also
Benzodiazipines
- Alprazolam
- Chlordiazepoxide
- Diazepam (Oral)
- Estazolam
- Flurazepam
- Lorazepam
- Midazolam
- Oxazepam
- Quazepam
- Temazepam
- Triazolam
Anticonvulsants Drugs
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Sedatives and Hypnotics
- Herbals
- Chamomile (Matricaria recutita)
- Hops (Humulus lupulus)
- Lavender (Lavandula angustifolia)
- Passionflower (Passiflora incarnata)
- Valerian (Valeriana officinalis)
- Melatonin and its Analogues
Miscellaneous Agents
- Buspirone
- Chloral hydrate
- Doxepin
- Meprobamate
- Sodium Oxybate (Narcolepsy Agent)
- Suvorexant
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