Ketotifen
Ketotifen
Overview
Ketotifen is a medication classified as a cycloheptathiophene derivative, known for its anti-allergic properties. It plays a significant role in managing allergic symptoms, particularly in the treatment of asthma and allergic rhinitis.
Chemical Composition and Properties
- Ketotifen is chemically a cycloheptathiophene derivative.
- It possesses both antihistaminic and mast cell stabilizing properties, making it effective in allergy management.
Mechanism of Action
- As an antihistamine, Ketotifen blocks histamine H1 receptors, reducing allergic symptoms.
- It also prevents the release of mediators from mast cells involved in allergic reactions.
Indications and Usage
- Primarily used for the prevention of asthma attacks.
- Also effective in treating allergic rhinitis and conjunctivitis.
- Can be used for chronic urticaria and other allergy-related conditions.
Dosage and Administration
- Available in various forms, including tablets, syrup, and eye drops.
- The dosage depends on the form of medication and the patient's age and condition.
Side Effects and Precautions
- Common side effects include drowsiness, dry mouth, and dizziness.
- Patients are advised not to operate heavy machinery or drive if they experience drowsiness.
- Should be used with caution in patients with liver or kidney impairment.
Pharmacokinetics
- Well-absorbed after oral administration.
- Metabolized in the liver and excreted primarily through the kidneys.
Interactions with Other Medications
- Can interact with other sedatives, alcohol, and certain antidepressants.
- Patients should consult with a healthcare provider before combining Ketotifen with other medications.
Research and Developments
- Ongoing research explores additional therapeutic uses and potential benefits of Ketotifen in treating other allergic conditions.
See Also
References
External Links
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