Amitriptylinoxide
Amitriptylinoxide
Amitriptylinoxide (pronounced: a-mi-trip-tyl-in-oxide) is a tricyclic antidepressant (TCA) that is used in the treatment of depression. It is a secondary amine TCA, similar to desipramine and nortriptyline.
Etymology
The term "Amitriptylinoxide" is derived from its chemical structure. "Amitriptyline" refers to the parent compound, a tricyclic antidepressant, and "oxide" refers to the addition of an oxygen atom in the chemical structure.
Pharmacology
Amitriptylinoxide acts by inhibiting the reuptake of serotonin and norepinephrine, two neurotransmitters in the brain. This increases the concentration of these neurotransmitters in the synaptic cleft, leading to an improvement in mood.
Related Terms
- Tricyclic antidepressant: A class of drugs that Amitriptylinoxide belongs to. They are named for their three-ring chemical structure.
- Serotonin: A neurotransmitter that is involved in the regulation of mood, appetite, and sleep. Amitriptylinoxide increases the concentration of serotonin in the brain.
- Norepinephrine: A neurotransmitter that is involved in the regulation of attention and responding actions. Amitriptylinoxide increases the concentration of norepinephrine in the brain.
- Desipramine: A secondary amine tricyclic antidepressant, similar to Amitriptylinoxide.
- Nortriptyline: A secondary amine tricyclic antidepressant, similar to Amitriptylinoxide.
External links
- Medical encyclopedia article on Amitriptylinoxide
- Wikipedia's article - Amitriptylinoxide
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