Paraldehyde
Paraldehyde
Paraldehyde (pronunciation: /ˌpærəˈldeɪhaɪd/) is a potent central nervous system depressant and sedative used in the treatment of severe insomnia and alcohol withdrawal syndrome.
Etymology
The term "paraldehyde" is derived from the Greek words "para", meaning "beside", and "aldehyde", a type of organic compound. It was first synthesized in 1829 by the German chemist Justus von Liebig.
Usage
Paraldehyde is primarily used as a sedative and hypnotic in the treatment of severe insomnia and alcohol withdrawal syndrome. It is also used as an anticonvulsant in the treatment of status epilepticus, a life-threatening condition characterized by continuous, prolonged seizures.
Pharmacology
Paraldehyde works by increasing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that inhibits the activity of the central nervous system. This results in a decrease in nervous tension and a calming effect.
Side Effects
Common side effects of paraldehyde include drowsiness, dizziness, and nausea. In rare cases, it can cause respiratory depression, a serious condition characterized by slow and ineffective breathing.
Related Terms
- Central nervous system
- Sedative
- Insomnia
- Alcohol withdrawal syndrome
- Status epilepticus
- Gamma-aminobutyric acid
- Respiratory depression
External links
- Medical encyclopedia article on Paraldehyde
- Wikipedia's article - Paraldehyde
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