Alprazolam

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Alprazolam (/ælˈpræzəlæm/), commonly known by the brand name Xanax, is a short-acting tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It is most commonly used in short term management of anxiety disorders, specifically panic disorder or generalized anxiety disorder (GAD).

Etymology

The name "Alprazolam" is a portmanteau of its key components: the alpr is derived from alpha and propiolactone, and the azolam signifies the azolobenzodiazepine compound.

Pharmacology

Alprazolam, like other benzodiazepines, binds to specific sites on the GABA_A receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, and amnestic properties.

Medical Uses

Alprazolam is used for the treatment of anxiety disorders and panic disorder. In the UK, alprazolam is recommended for the short-term treatment (2–4 weeks) of severe acute anxiety.

Side Effects

Common side effects of alprazolam include drowsiness, fatigue, and ataxia. More severe side effects may include hallucinations, jaundice, and paradoxical reactions, such as aggression and rage.

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