Magnolol

From WikiMD's medical encyclopedia

Magnolol is an organic compound that is classified as a lignan. It is a bioactive compound found in the bark of the Houpu magnolia (Magnolia officinalis) or in Magnolia grandiflora. The compound, (+)-magnolol, is known for its antioxidant and anti-inflammatory effects.

Chemical Structure

Magnolol is a biphenolic compound, which means it has two phenol groups. Its chemical formula is C18H18O2. The structure of magnolol consists of two aromatic rings, which are connected by a two-carbon bridge. This bridge has a hydroxyl group attached to it.

Pharmacology

Magnolol has been studied for its potential therapeutic effects. It has been found to have anti-inflammatory, antioxidant, anti-cancer, and neuroprotective effects. It is also being studied for its potential use in the treatment of Alzheimer's disease.

Uses

Magnolol is used in traditional Chinese medicine, where it is known as Houpu or Hou Po. It is used to treat a variety of conditions, including gastrointestinal disorders, respiratory disorders, and anxiety.

Safety

While magnolol is generally considered safe, it can cause side effects such as dizziness, headache, and skin rash. It can also interact with other medications, so it should be used with caution.

See Also

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Magnolol

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Contributors: Prab R. Tumpati, MD