Stiripentol

Stiripentol (pronounced: sti-ri-pen-tol) is a type of anticonvulsant medication used primarily in the treatment of Dravet syndrome, a rare and catastrophic form of intractable epilepsy that begins in infancy.

Etymology

The term "Stiripentol" is derived from its chemical name, 4,4-dimethyl-1-[3,4-(methylene-dioxy)-phenyl]-1-penten-3-ol.

Usage

Stiripentol is used in conjunction with other anticonvulsant medications such as clobazam and valproate to manage seizures in patients with Dravet syndrome. It is not typically used as a standalone treatment, but rather as part of a comprehensive treatment plan.

Mechanism of Action

Stiripentol works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that inhibits brain signals and decreases activity in the nervous system, helping to reduce the frequency and intensity of seizures.

Side Effects

Like all medications, Stiripentol can cause side effects. Common side effects include drowsiness, loss of appetite, weight loss, and nausea. More serious side effects can include changes in mood or behavior, hallucinations, and thoughts of suicide.

Related Terms

• Anticonvulsant
• Dravet syndrome
• Clobazam
• Valproate
• Gamma-aminobutyric acid

External links

• Medical encyclopedia article on Stiripentol
• Wikipedia's article - Stiripentol

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