Honokiol

Honokiol is a lignan isolated from the bark, seed cones, and leaves of trees belonging to the genus Magnolia. It has been identified as one of the chemical compounds in some traditional eastern herbal medicines along with magnolol, 5,5'-diallyl-1,1'-biphenyl-2,2'-diol, obovatol, and ecdysterone.

History

Honokiol has been extracted from a number of species of Magnolia native to many regions of the globe. Magnolia grandiflora, which is native to the American South, as well as Mexican species like Magnolia dealbata have been found to be sources of honokiol. Traditionally in Asian medicine, the Magnolia biondii, Magnolia obovata, and Magnolia officinalis are commonly used.

Pharmacology

Honokiol is a neolignan, a type of phenolic compound. It is a highly active compound extracted from Magnolia and has been shown to have a variety of beneficial effects in preclinical studies.

Medical uses

Honokiol has been used in the traditional Japanese medicine Saiboku-to as an anxiolytic, antithrombotic, antidepressant, antiemetic, and bronchodilator. It has also been studied for its potential use in treating various diseases, including cancer, Alzheimer's disease, anxiety, and thrombosis.

Side effects

As with any medication, honokiol can have side effects. These can include dizziness, fatigue, and nausea. It is important to consult with a healthcare provider before starting any new medication.

See also

• Magnolol
• Saiboku-to
• Magnolia

References

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  Magnolol purification process
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  Magnolia grandiflora fruit
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  Magnolia hypoleuca
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  GABAA receptor binding sites